Abstract

Modern research confirms the existence of a close relationship between the gut and the brain, known as the "gut-brain axis" (Zhao et al., 2023). In patients who have undergone intestinal resection, changes in the digestive tract function can significantly affect cognitive functions and neurological status. One of the key factors playing an important role in these disruptions is the increased permeability of the intestinal wall, which leads to impaired absorption of many vitamins and micronutrients. This disorder, known as the "leaky gut syndrome," can worsen not only metabolism but also neurobiological processes (Wang et al., 2023).

After intestinal resection, the ability of the intestine to absorb nutrients is often reduced, leading to deficiencies in vitamins, particularly B vitamins and vitamin D. B vitamins are essential for the proper functioning of the nervous system and homocysteine metabolism, and their deficiency can contribute to cognitive impairments (Meyer et al., 2022). Vitamin D plays an important role in maintaining neuroplasticity and regulating inflammatory processes in the brain (Zhao et al., 2023).

This article presents a clinical case of a patient who underwent multiple intestinal resections, in whom, against the background of increased intestinal permeability and impaired nutrient absorption, there is progressive cognitive decline and the development of secondary segmental dystonia. This case highlights the importance of considering changes in gut microbiota and nutrient absorption disorders when assessing neurological symptoms in patients after intestinal resections.